Each kit has a dried blood spot collection device comes with an option 15 minute, web-based cognitive function test. The test is immediately accessible after the kit is registered online. When the blood work has finished processing, you will receive notification of the entire report being ready for viewing, downloading, or printing.
DRIED BLOOD SPOT SAMPLE
BrainSpan measures 29 fatty acids including the Omega-3 Index, the AA/EPA Ratio (Omega-6 to Omega-3 variant) and Palmitic Acid. In addition, 6 wellness summary areas are provided alongside the BrainSpan Index.
COGNITIVE FUNCTION TEST
This cognitive function test reliably measures memory, attention, cognitive flexibility, and processing speed.The test is one of the most well-validated cognitive function tests in the world with over 450 studies to date.
A Simple 3-Step Process
First you will perform a simple fingerstick blood test placing a few drops of blood on a small card. We process samples within 5-7 days of receiving them.
Next, a 15-minute, web-based cognitive test will evaluate your performance in areas to include memory, processing speed, attention, and cognitive flexibility.
Our report will provide powerful insights that are clear and easy for you to understand. The report allows you to track your results over time so you can track changes early.
The BrainSpan Report Metrics
FATTY ACID MARKERS
COGNITIVE FUNCTION MARKERS
FATTY ACID MARKERS
OMEGA-3 INDEX: REFLECTS MEMBRANE INTEGRITY, NEUROGENESIS, AND LOWER INFLAMMATORY CLIMATE
Omega-3 fatty acids are the building blocks of the brain, determining the brain's integrity and ability to perform. They are to your brain cells what calcium is to your bones -- or what protein is to your muscles. EPA/DHA are made inefficiently from ALA, so it is now critical to obtain them directly by eating fish or taking fish oil. The most important factor is how much is absorbed by your blood cells. This is a fact that many scientific studies on fish and fish oil miss leading to confusion about the benefits of fish/fish oil.
AA/EPA RATIO: A MEASURE OF CELL CLIMATE AND THE EQUILIBRIUM IN PRO/ANTI INFLAMMATORY HORMONES
Omega-6s (specifically one called "AA") tend to increase pain, inflammation and clotting, whereas Omega-3s such as EPA tend to decrease inflammation and increase blood flow. Both are considered by academics and regulatory bodies as "essential nutrients"--that is, we must get them from our diet for survival--we cannot manufacture them on our own. Balancing these fatty acids is foundational to properly regulating your body's inflammatory response.
PALMITIC ACID: REFLECTS EXCESS GLUCOSE TURNING TO FAT BECAUSE OF GLUCOSE LEVELS BEYOND THE ENERGY REQUIREMENTS OF THE CELL
Excessive palmitic acid (usually from a diet high in simple carbohydrates) is generated from excess carbohydrates that we do not burn through our cellular metabolic cycle (called the "Krebs Cycle"). High levels are associated with harmful fatty acid changes in the cell wall that can suppress hormone response and diminish proper cell-to-cell signaling. Maintaining optimal palmitic acid levels helps normalize leptin and insulin signaling, which helps regulate your metabolism, increases your energy, and improves neurotransmitter communication.
COGNITIVE FUNCTION MARKERS
Working memory is the process whereby your brain is able to temporarily store information in the moment and recall it when you need it. Poor working memory may be associated with nutritional deficits in the cells of the hippocampus –the part of the brain that stores memories. Poor working memory scores may suggest brain cell nutrient deficiencies, inflammation, insufficient neuronal connections, or poor quality sleep.
To efficiently sustain your attention and 'tune out' competing distractions, your brain must produce specific neurotransmitters. However, your brain requires adequate nutrients to create these neurotransmitters. Attentional problems may be associated with deficiencies in the pre-frontal region of the brain, which controls selective attention, impulsivity, and motivation. These impairments may be caused from nutrient deficiencies, stress, or inflammation.
Flexible attention is your capacity to rapidly adapt your thinking based on new information and not get stuck in compulsive behavior. Your brain must be able to reorganize itself by forming new neural connections. Poor flexible attention scores may be due to a decreased production of the neurotransmitters serotonin and GABA.
Processing speed is the pace at which you take in information, make sense of it and begin to respond. It has nothing to do with how smart you are -- just how fast you can take in and use information. Slow processing speed is associated with inefficient connections in the brain's gray matter. These weak connections may be due to nutrient deficiencies in brain cells, limited production of vital neurotransmitters, chronic stress, lack of quality sleep, and toxins in your diet (such as refined sugars and processed foods).
Many fatty acids are much more important when examined in context with several other fatty acids; as they also exist within our diets. The 6 different clinical summary scores below are based on over 20 different fatty acids as well as age, gender, and cognitive functional scores. The result is a single graphic that tells a clear and powerful message of one's health status based on specific clinical areas that are likely to be extremely relevant to the client's current health status. The result is immediate understanding of the link between specific behaviors, nutritional markers, and the client's present or future health conditions.
ACTIONABLE METRIC SUMMARY
The actionable-metric trend summary page is the capstone of the report that highly influences compliance and adherence through its actionability as well as its emphasis on demonstrating progress; both key to create lasting behavioral change.For practitioners, it's also customizable at the time you create your account (It can also be changed later by simply submitting a ticket request). This is single page, two-column graphic; with metrics on one side, and "anti-dote" on the other. Making it clear to the majority of clients that want to know the "what" and "why" behind changes being asked of them. Down the middle we place the trend-line from test to test (up to 4 test values at a time).
Note: You can download full reports including different customizable, branded metric summary pages below this section.
DOWNLOAD A SAMPLE REPORT
And choose your option for the type of summary page.
Daniel T. Johnston, MD, MPH
Founder and CEO, BrainSpan
LEARN MORE THROUGH A 5 MIN VIDEO
What is BrainSpan?
Dr. Johnston takes us through the key features and process of BrainSpan.